Article updated: 2024 Mar 4 / Author Leslie Griver, Robert Henry

How To Lower Weed Tolerance 2 Times Faster With Science

You can lower weed tolerance two times faster following simple methods based on scientific researches.

We’ll tell you these methods, but at first, it’s essential to understand why weed tolerance builds up.

Why weed tolerance builds up

Tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, works by activating the cannabinoid receptor CB1 located on the body’s neurons.

A 2016 study found that regular weed smokers had 20% fewer CB1 receptors in their brains than non-smokers.

The study split the participants into two groups. One group had to quit smoking for two days. Other group participants had to quit smoking for four weeks.

The study results showed that CB1 receptors began to restore after just two days of abstinence and returned to almost normal levels in four weeks.

After four weeks of abstinence, researchers did not find a difference between past smokers and non-smokers.

How long to quit weed to lower tolerance

As the above study showed – you need to quit smoking weed for over four weeks for CB1 receptors and weed tolerance to restore normal levels.

Why does it take so long?

When you quit smoking, THC and its metabolites are still present in your system. THC is highly fat-soluble, and it binds to body fat cells.

After that, it is slowly released into the blood. Even if you don’t consume cannabis, THC is present in your blood and affects your brain.

If you need more details, read this guide: The Ultimate Guide to Marijuana Metabolism

For example, this study shows that food deprivation, stress, or excessive exercise cause THC release from fat stores back into the blood. It causes ‘reintoxication’ because of high levels of THC in the blood.

How to lower weed tolerance faster

To lower weed tolerance, you need to prevent your brain from contact with THC and its metabolites.

The only way you can do it is by removing THC from your system as fast as possible. When your system is clean from marijuana, your brain will not receive THC, and CB1 receptors will restore.

You have three ways to get weed out of your system:

Doing all this will remove THC from your system and thus lower your weed tolerance faster.

Step-by-step instructions to lower weed tolerance

You’ll need:

If you need a detailed explanation of how each of these elements helps you to clean your system of THC, read this guide: THC Detox Guide. How To Get Weed Out Of Your System

Follow a healthy diet plan.

To burn body fat, you need to eat healthy food. You also need to eat fewer calories than you spend.

The detailed meal plan depends on your daily calorie requirements and food preferences. First, you need to calculate the number of required calories and then modify your meal plan to consume fewer calories than needed.

You can find a good calorie calculator and sample meal plans here:


Exercising promotes the burning of body fat and the release of THC.

The simplest way to add exercise to your daily routine is to walk for at least 60 minutes. You can also add low-intensity cardio training.

Remember that you also need to do it for at least 60 minutes.

This is because our body uses the energy saved as glycogen in our muscles and liver. There’s enough energy for ~45 minutes of activity.

After this energy is depleted, our body starts to get energy from the body fat.

Activated charcoal

Take 1000mg of activated charcoal twice daily. It absorbs THC in the intestines and prevents its reabsorption back into the blood.

St. John’s Wort

Take 300mg of St. John’s Wort extract three times daily.

It is the most famous herb for improving the activity of enzymes responsible for THC metabolism.

It is well researched, and several studies confirm its properties.

Apple cider vinegar

Scientific studies confirm that vinegar helps to lose more body fat. Consuming it along with proper diet and exercise will make you lose more body fat at the same time.

Take 15ml of apple cider vinegar with 0.5l of water twice daily.

Important: We do not provide medical advice. The provided information is intended for informational purposes only and is not a substitute for professional medical consultation, diagnosis, or treatment.

How much time will it take to lower weed tolerance with detoxification?

Here’s a chart of THC metabolites in the blood over time.

The red line is the concentration of THC in blood without any detoxification.

The blue line is the THC concentration in blood when you follow the detox steps that we listed here.

The green line is the concentration when you use a 7-day detox drink or kit. The spike on a green line shows that THC is rapidly released from the fat cells. This temporarily increases the concentration of THC in the blood, but it is quickly metabolized and excreted.

how to lower weed tolerance with detox

So, as you see, you can lower weed tolerance almost two times faster if you follow the provided THC detox steps.

If you’ll use a 7-day detox kit or drink, you will lower tolerance in 7 days.

How to lower weed tolerance without a break

Consume less cannabis

Some of you start consuming weed in the early morning. It’s just a habit you are accustomed to. Well, give it a rest.

When you refrain from consuming cannabis first thing in the morning, your body will slowly begin to adjust.

Wait until the afternoon for your first toke of the day. After a few days, wait until the evening for your initial session.

You will enjoy the experience more, and you’ll cut back on your tolerance level.

Use less per session.

Use smaller papers or roll pinner joints for a couple of months. If you are into blunts, move to joints.

If you dab, try to use another method or smaller amounts of wax.

Use a different weed strain.

Different strains contain different amounts of THC. So switching strains will help you to adjust your tolerance. Try to use a lower THC strain.

If you prefer heavy indica, go with a hybrid strain or something not as heavy.

Giving your body something new will help you to restore your receptors and adjust your tolerance.

Use chillum

Chillums are designed for on-the-go consumption and are great for reducing your intake.

These are personal tools not meant to be passed around. So you may be consuming by yourself a little more, but you might find you are using much less.

Take longer breaks in between smokes.

If you’re smoking cannabis ten times a day, cutting that down to five will help with your tolerance break.

Just wait two hours instead of one. This will cut your marijuana consumption down without interfering with your regular THC routine.

You may find that you don’t even need to take that many hits of marijuana to feel the body receptors start to do their part. It’s just become a habit.